HitPredict

Interactor 1: ATF2 (P16951)
Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (MXBP protein) (cAMP response element-binding protein CRE-BP1)
Gene: ATF2

Interactor 2: MK09 (Q9WTU6)
Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)
Gene: Mapk9

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15192015
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001934 - positive regulation of protein phosphorylation GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0007254 - JNK cascade
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 487 Mm			1 423
+	Hs
		547743 ATF2_HUMAN (1-477): 7.42e-134: 398: 99.58		MK09_HUMAN (1-423): 5.68e-170: 484: 96.70
+	Hs
		547757 ATF2_HUMAN (1-477): 7.42e-134: 398: 99.58		MK10_HUMAN (1-423): 5.69e-160: 460: 84.51
+	Hs
		547742 ATF2_HUMAN (1-477): 7.42e-134: 398: 99.58		MK08_HUMAN (1-423): 4.71e-156: 449: 81.27
+	Mm
		562982 ATF2_MOUSE (1-487): 2.97e-130: 388: 100.00		MK08_MOUSE (1-378): 8.57e-149: 429: 84.39
+	Hs
		568251 ATF7_HUMAN (1-482): 7.98e-109: 333: 54.69		MK08_HUMAN (1-423): 4.71e-156: 449: 81.27
+	Hs
		173828 ATF2_HUMAN (1-477): 7.42e-134: 398: 99.58		MK13_HUMAN (10-376): 8.65e-130: 380: 46.61
+	Hs
		547811 ATF2_HUMAN (1-477): 7.42e-134: 398: 99.58		MK14_HUMAN (4-366): 4.99e-130: 380: 48.91
+	Mm
		562973 ATF2_MOUSE (1-487): 2.97e-130: 388: 100.00		MK14_MOUSE (4-366): 2.3e-130: 381: 48.91
+	Rn
		102456 ATF2_RAT (1-487): 3.94e-130: 387: 98.77		G3V617_RAT (4-366): 1.38e-130: 381: 48.91
+	Hs
		547805 ATF2_HUMAN (1-477): 7.42e-134: 398: 99.58		MK11_HUMAN (10-363): 1.6e-111: 333: 48.88
+	Mm
		562985 ATF2_MOUSE (1-487): 2.97e-130: 388: 100.00		MK11_MOUSE (10-364): 1.08e-110: 331: 48.75
+	Hs
		547713 ATF2_HUMAN (1-477): 7.42e-134: 398: 99.58		MK01_HUMAN (15-364): 3.7e-86: 268: 41.34
+	Hs
		547709 ATF2_HUMAN (1-477): 7.42e-134: 398: 99.58		MK03_HUMAN (15-375): 2.95e-85: 266: 41.08
+	Mm
		562980 ATF2_MOUSE (1-487): 2.97e-130: 388: 100.00		MK03_MOUSE (20-370): 3.27e-86: 269: 41.39
+	Mm
		562975 ATF2_MOUSE (1-487): 2.97e-130: 388: 100.00		MK01_MOUSE (15-364): 8.44e-86: 267: 41.06
+	Hs
		566735 JUNB_HUMAN (69-405): 4.99e-44: 160: 15.08		MK09_HUMAN (1-423): 5.68e-170: 484: 96.70
+	Rn
		567364 JUN_RAT (113-413): 5.98e-41: 151: 18.15		MK09_RAT (1-423): 7.26e-172: 489: 97.87
+	Rn
		567365 JUN_RAT (113-413): 5.98e-41: 151: 18.15		MK10_RAT (1-423): 6.7e-160: 460: 84.51
+	Hs
		566734 JUNB_HUMAN (69-405): 4.99e-44: 160: 15.08		MK08_HUMAN (1-423): 4.71e-156: 449: 81.27
+	Rn
		567363 JUN_RAT (113-413): 5.98e-41: 151: 18.15		MK08_RAT (1-407): 6.01e-152: 438: 81.27