HitPredict

Interactor 1: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Interactor 2: KS6A3 (P51812)
Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)
Gene: RPS6KA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 740
+	Hs
		503719 HSP7C_HUMAN (4-615): 0: 940: 79.25		KS6A3_HUMAN (1-740): 0: 844: 100.00
+	Hs
		564080 HSP76_HUMAN (1-643): 0: 970: 100.00		KS6A1_HUMAN (1-740): 0: 783: 77.90
+	Hs
		504119 HSP7C_HUMAN (4-615): 0: 940: 79.25		KS6A1_HUMAN (1-740): 0: 783: 77.90
+	Hs
		564016 HSP76_HUMAN (1-643): 0: 970: 100.00		AKT1_HUMAN (327-739): 2.87e-125: 383: 21.02
+	Hs
		564201 HSP76_HUMAN (1-643): 0: 970: 100.00		KS6B2_HUMAN (419-727): 5.97e-118: 364: 29.66
+	Hs
		503528 HSP7C_HUMAN (4-615): 0: 940: 79.25		AKT1_HUMAN (327-739): 2.87e-125: 383: 21.02
+	Hs
		504896 HSP7C_HUMAN (4-615): 0: 940: 79.25		KS6B2_HUMAN (419-727): 5.97e-118: 364: 29.66