HitPredict

Interactor 1: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Interactor 2: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 81
+	Hs
		713983 HS71L_HUMAN (1-643): 0: 960: 79.32		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Hs
		474905 HSP7C_HUMAN (4-615): 0: 940: 79.25		UBB_HUMAN (1-76): 2.4e-30: 107: 57.90
+	Dm
		505044 HSP7D_DROME (4-614): 0: 923: 79.38		RS27A_DROME (1-77): 3.39e-36: 121: 57.14
+	Hs
		504136 HSP7C_HUMAN (4-615): 0: 940: 79.25		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Ce
		450538 HSP1_CAEEL (4-643): 0: 922: 77.07		NEDD8_CAEEL (1-77): 7.56e-34: 112: 87.01