HitPredict

Interactor 1: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Interactor 2: CDK20 (Q8IZL9)
Cyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H) (Cyclin-kinase-activating kinase p42)
Gene: CDK20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 346
+	Hs
		713942 HS71L_HUMAN (1-643): 0: 960: 79.32		CDK3_HUMAN (1-308): 3.83e-138: 395: 44.66
+	Hs
		503460 HSP7C_HUMAN (4-615): 0: 940: 79.25		CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10
+	Hs
		564038 HSP76_HUMAN (1-643): 0: 970: 100.00		CDK7_HUMAN (3-304): 2.01e-127: 370: 42.62
+	Hs
		503902 HSP7C_HUMAN (4-615): 0: 940: 79.25		CDK3_HUMAN (1-308): 3.83e-138: 395: 44.66
+	Hs
		504378 HSP7C_HUMAN (4-615): 0: 940: 79.25		CDK20_HUMAN (1-346): 2.32e-134: 387: 100.00
+	Hs
		871660 HSP72_HUMAN (3-643): 0: 925: 77.45		CDK20_HUMAN (1-346): 2.32e-134: 387: 100.00
+	Hs
		503702 HSP7C_HUMAN (4-615): 0: 940: 79.25		CDK7_HUMAN (3-304): 2.01e-127: 370: 42.62
+	Hs
		483754 HS71A_HUMAN (5-643): 0: 934: 82.16		CDK7_HUMAN (3-304): 2.01e-127: 370: 42.62
+	At
		612295 HS701_ARATH (5-643): 0: 928: 70.28		CDKA1_ARATH (1-292): 1.49e-129: 373: 42.71
+	Mm
		509463 HSP72_MOUSE (3-614): 0: 920: 79.32		CDK1_MOUSE (1-292): 3.11e-130: 375: 42.52
+	Dm
		505057 HSP7D_DROME (4-614): 0: 923: 79.38		Q24216_DROME (2-315): 1.1e-76: 241: 40.88