HitPredict

Interactor 1: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Interactor 2: BAG1 (Q99933)
BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1)
Gene: BAG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	33957083, 34428256
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAG~HSP70
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0051085 - chaperone cofactor-dependent protein refolding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 345
+	Hs
		1120588 Q53FC7_HUMAN (1-643): 0: 965: 99.22		BAG1_HUMAN (1-345): 4.2e-176: 493: 100.00
+	Mm
		571857 HS71B_MOUSE (5-643): 0: 938: 80.63		BAG1_MOUSE (1-345): 0: 520: 71.27
+	Rn
		69526 HSP7C_RAT (4-615): 0: 939: 79.25		BAG1_RAT (1-345): 0: 518: 69.83
+	Hs
		714058 HS71L_HUMAN (1-643): 0: 960: 79.32		BAG1_HUMAN (1-345): 4.2e-176: 493: 100.00
+	Hs
		504647 HSP7C_HUMAN (4-615): 0: 940: 79.25		BAG1_HUMAN (1-345): 4.2e-176: 493: 100.00
+	Hs
		871754 HSP72_HUMAN (3-643): 0: 925: 77.45		BAG1_HUMAN (1-345): 4.2e-176: 493: 100.00