HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: AT2B1 (P20020)
Plasma membrane calcium-transporting ATPase 1 (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 1) (PMCA1) (Plasma membrane calcium pump isoform 1)
Gene: ATP2B1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 1220
+	Hs
		588672 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		AT2B1_HUMAN (1-1220): 0: 1275: 100.00
+	Hs
		588588 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		AT2B1_HUMAN (1-1220): 0: 1275: 100.00
+	Hs
		588583 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		AT2B1_HUMAN (1-1220): 0: 1275: 100.00
+	Hs
		588572 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		AT2B1_HUMAN (1-1220): 0: 1275: 100.00
+	Hs
		588576 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		AT2B1_HUMAN (1-1220): 0: 1275: 100.00
+	Hs
		545205 RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03		AT2B1_HUMAN (1-1220): 0: 1275: 100.00
+	Hs
		588581 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		AT2B1_HUMAN (1-1220): 0: 1275: 100.00
+	Hs
		619221 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		AT2B4_HUMAN (7-1220): 0: 1207: 73.15
+	Hs
		393348 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		AT1A1_HUMAN (41-1082): 0: 770: 22.46
+	Hs
		393020 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		AT1A1_HUMAN (41-1082): 0: 770: 22.46
+	Hs
		393158 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		AT1A1_HUMAN (41-1082): 0: 770: 22.46
+	Hs
		393152 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		AT1A1_HUMAN (41-1082): 0: 770: 22.46
+	Hs
		393131 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		AT1A1_HUMAN (41-1082): 0: 770: 22.46
+	Hs
		393135 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		AT1A1_HUMAN (41-1082): 0: 770: 22.46
+	Hs
		393014 RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03		AT1A1_HUMAN (41-1082): 0: 770: 22.46
+	Hs
		530865 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		AT1A3_HUMAN (35-1082): 0: 761: 22.15
+	Hs
		393129 RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67		AT1A1_HUMAN (41-1082): 0: 770: 22.46
+	Hs
		393147 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		AT1A1_HUMAN (41-1082): 0: 770: 22.46
+	Hs
		561551 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		AT2A2_HUMAN (50-1078): 0: 759: 25.44
+	Hs
		561542 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		AT2A2_HUMAN (50-1078): 0: 759: 25.44