HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: ITA6 (P23229)
Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)]
Gene: ITGA6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 1130
+	Hs
		613279 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		613241 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		613239 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		419236 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		639881 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		ITA3_HUMAN (7-1108): 0: 936: 34.72
+	Hs
		443098 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		419150 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		419191 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		419189 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		530601 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		ITA4_HUMAN (2-1096): 0: 865: 23.40
+	Hs
		443030 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		443071 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		443068 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		880220 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		ITA1_HUMAN (161-1090): 0: 646: 21.01
+	Hs
		564464 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		ITA1_HUMAN (161-1090): 0: 646: 21.01
+	Hs
		880212 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		ITA1_HUMAN (161-1090): 0: 646: 21.01
+	Hs
		880211 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		ITA1_HUMAN (161-1090): 0: 646: 21.01
+	Hs
		564407 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Hs
		566875 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Hs
		566873 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22