HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: BORG5 (Q00587)
Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55)
Gene: CDC42EP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PBD~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0008360 - regulation of cell shape
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 391
+	Hs
		960657 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Hs
		950927 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Hs
		925198 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Hs
		893907 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Hs
		900382 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Hs
		545325 RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Hs
		915611 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00
+	Hs
		1330288 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54
+	Hs
		564682 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54
+	Hs
		951333 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54
+	Hs
		925610 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54
+	Hs
		894420 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54
+	Hs
		900891 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54
+	Hs
		545611 RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03		BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54
+	Hs
		915970 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54
+	Hs
		150121 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		BORG1_HUMAN (33-217): 2.72e-53: 177: 32.09
+	Hs
		150124 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		BORG1_HUMAN (33-217): 2.72e-53: 177: 32.09
+	Hs
		564729 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		BORG2_HUMAN (33-218): 6.27e-48: 165: 27.85
+	Hs
		894571 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		BORG2_HUMAN (33-218): 6.27e-48: 165: 27.85
+	Hs
		894139 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		BORG3_HUMAN (38-67): 9.1e-09: 55.7: 86.67