HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: RGPA2 (Q2PPJ7)
Ral GTPase-activating protein subunit alpha-2 (250 kDa substrate of Akt) (AS250) (p220)
Gene: RALGAPA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rap_GAP~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 1873
+	Hs
		1102438 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		RGPA2_HUMAN (1-1873): 0: 2869: 100.00
+	Hs
		951036 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		RGPA2_HUMAN (1-1873): 0: 2869: 100.00
+	Hs
		1151779 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		RGPA1_HUMAN (1-851): 0: 1225: 48.66
+	Hs
		564573 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		RGPA1_HUMAN (1-851): 0: 1225: 48.66
+	Hs
		951081 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		RGPA1_HUMAN (1-851): 0: 1225: 48.66
+	Hs
		925359 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		RGPA1_HUMAN (1-851): 0: 1225: 48.66
+	Hs
		894131 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		RGPA1_HUMAN (1-851): 0: 1225: 48.66
+	Hs
		900583 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		RGPA1_HUMAN (1-851): 0: 1225: 48.66
+	Hs
		1203741 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		RLGPB_HUMAN (993-1802): 3.58e-139: 473: 17.54
+	Hs
		564595 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		RLGPB_HUMAN (993-1802): 3.58e-139: 473: 17.54
+	Hs
		951126 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		RLGPB_HUMAN (993-1802): 3.58e-139: 473: 17.54
+	Hs
		925407 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		RLGPB_HUMAN (993-1802): 3.58e-139: 473: 17.54
+	Hs
		894180 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		RLGPB_HUMAN (993-1802): 3.58e-139: 473: 17.54
+	Hs
		900651 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		RLGPB_HUMAN (993-1802): 3.58e-139: 473: 17.54
+	Hs
		196428 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		SI1L1_HUMAN (1544-1861): 3.5e-92: 335: 19.45
+	Hs
		925514 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		SIPA1_HUMAN (1545-1859): 7.89e-90: 319: 21.23
+	Hs
		900790 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		SIPA1_HUMAN (1545-1859): 7.89e-90: 319: 21.23
+	Hs
		230233 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		SI1L3_HUMAN (1534-1859): 2.76e-83: 306: 20.35
+	Dm
		776929 RAC1_DROME (10-195): 1.67e-76: 229: 63.98		X2JDH0_DROME (1505-1859): 1.71e-80: 297: 18.06
+	Dm
		776932 RAC1_DROME (10-195): 1.67e-76: 229: 63.98		X2JJU0_DROME (1505-1859): 1.6e-80: 297: 18.06