HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: MICA3 (Q7RTP6)
[F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3)
Gene: MICAL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~bMERB_dom
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 2002
+	Hs
		1186089 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		MICA3_HUMAN (1-2002): 0: 1314: 100.00
+	Hs
		925387 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		MICA3_HUMAN (1-2002): 0: 1314: 100.00
+	Hs
		963416 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56
+	Hs
		164665 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		SPTN2_HUMAN (433-1216): 1.38e-79: 295: 14.86
+	Hs
		564483 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56
+	Hs
		950929 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56
+	Hs
		925201 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56
+	Hs
		164564 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		SPTN2_HUMAN (433-1216): 1.38e-79: 295: 14.86
+	Hs
		164602 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		SPTN2_HUMAN (433-1216): 1.38e-79: 295: 14.86
+	Hs
		164599 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		SPTN2_HUMAN (433-1216): 1.38e-79: 295: 14.86
+	Hs
		1242508 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		EHBP1_HUMAN (520-762): 2.11e-37: 156: 22.53
+	Dd
		710112 RAC1A_DICDI (10-204): 4.13e-79: 236: 59.49		CTXA_DICDI (506-781): 1.29e-54: 200: 21.75
+	Hs
		564615 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		EHBP1_HUMAN (520-762): 2.11e-37: 156: 22.53
+	Hs
		1232332 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		MILK1_HUMAN (715-885): 2.96e-16: 87.2: 21.14
+	Ce
		136794 CDC42_CAEEL (10-193): 3.51e-91: 266: 67.94		UNC89_CAEEL (1306-1897): 2.14e-29: 131: 11.73
+	Hs
		951163 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		EHBP1_HUMAN (520-762): 2.11e-37: 156: 22.53
+	Hs
		925443 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		EHBP1_HUMAN (520-762): 2.11e-37: 156: 22.53
+	Hs
		564610 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		MILK1_HUMAN (715-885): 2.96e-16: 87.2: 21.14
+	Hs
		951148 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		MILK1_HUMAN (715-885): 2.96e-16: 87.2: 21.14
+	Hs
		925433 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		MILK1_HUMAN (715-885): 2.96e-16: 87.2: 21.14