HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: IQGA3 (Q86VI3)
Ras GTPase-activating-like protein IQGAP3
Gene: IQGAP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 1631
+	Hs
		1201453 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		IQGA3_HUMAN (1-1631): 0: 1709: 100.00
+	Hs
		809436 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		IQGA1_HUMAN (6-1631): 0: 1574: 58.99
+	Hs
		564448 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		IQGA1_HUMAN (6-1631): 0: 1574: 58.99
+	Hs
		809264 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		IQGA1_HUMAN (6-1631): 0: 1574: 58.99
+	Mm
		925821 RAC1_MOUSE (10-195): 4.15e-80: 238: 63.98		IQGA1_MOUSE (7-1631): 0: 1543: 58.85
+	Hs
		1040058 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		IQGA2_HUMAN (86-1631): 0: 1356: 42.50
+	Hs
		564517 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		IQGA2_HUMAN (86-1631): 0: 1356: 42.50
+	Hs
		950977 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		IQGA2_HUMAN (86-1631): 0: 1356: 42.50
+	Hs
		1056349 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		RASA3_HUMAN (841-1504): 2.12e-105: 359: 13.68
+	Hs
		1330979 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		NGAP_HUMAN (1000-1453): 5.22e-81: 294: 17.18
+	Hs
		564757 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		MYO5A_HUMAN (685-1556): 7.11e-89: 323: 14.90
+	Hs
		1139212 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		DAB2P_HUMAN (1000-1424): 2.56e-68: 255: 15.03
+	Hs
		564728 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		NGAP_HUMAN (1000-1453): 5.22e-81: 294: 17.18
+	Hs
		951447 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		NGAP_HUMAN (1000-1453): 5.22e-81: 294: 17.18
+	Gg
		1141019 Q6LC82_CHICK (10-195): 4.15e-80: 238: 63.98		ARHG6_CHICK (37-448): 7.38e-77: 274: 11.83
+	Hs
		951073 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		DAB2P_HUMAN (1000-1424): 2.56e-68: 255: 15.03
+	Hs
		598525 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		NF1_HUMAN (967-1301): 9.74e-45: 181: 21.57
+	Hs
		564412 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		NF1_HUMAN (967-1301): 9.74e-45: 181: 21.57
+	Hs
		598457 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		NF1_HUMAN (967-1301): 9.74e-45: 181: 21.57
+	Sc
		580334 CDC42_YEAST (10-185): 5.8e-85: 251: 66.48		IQG1_YEAST (31-265): 2.42e-26: 120: 25.83