HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: MINK1 (Q8N4C8)
Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)
Gene: MINK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 1332
+	Hs
		1233542 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		MINK1_HUMAN (1-1332): 0: 1277: 100.00
+	Hs
		925434 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		MINK1_HUMAN (1-1332): 0: 1277: 100.00
+	Mm
		925783 RAC1_MOUSE (10-195): 4.15e-80: 238: 63.98		TNIK_MOUSE (1-1332): 0: 1112: 62.60
+	Hs
		324877 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		324789 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		324783 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		564571 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		MRCKG_HUMAN (6-1299): 0: 652: 16.34
+	Hs
		925356 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		MRCKG_HUMAN (6-1299): 0: 652: 16.34
+	Hs
		894128 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		MRCKG_HUMAN (6-1299): 0: 652: 16.34
+	Hs
		1183120 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		MARK2_HUMAN (8-747): 3.42e-132: 427: 14.86
+	Hs
		564584 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		MARK2_HUMAN (8-747): 3.42e-132: 427: 14.86
+	Hs
		951102 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		MARK2_HUMAN (8-747): 3.42e-132: 427: 14.86
+	Hs
		925384 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		MARK2_HUMAN (8-747): 3.42e-132: 427: 14.86
+	Hs
		894157 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		MARK2_HUMAN (8-747): 3.42e-132: 427: 14.86
+	Hs
		951023 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		M3K11_HUMAN (26-779): 1.45e-120: 397: 21.38
+	Hs
		925309 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		M3K11_HUMAN (26-779): 1.45e-120: 397: 21.38
+	Hs
		894058 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		M3K11_HUMAN (26-779): 1.45e-120: 397: 21.38
+	Hs
		925212 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		M3K10_HUMAN (21-845): 1.48e-113: 381: 19.26
+	Hs
		893917 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		M3K10_HUMAN (21-845): 1.48e-113: 381: 19.26
+	Hs
		925763 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		M4K5_HUMAN (5-307): 6.97e-71: 257: 45.60