HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: NECT2 (Q92692)
Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112)
Gene: NECTIN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 538
+	Hs
		1269124 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		1330932 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Hs
		951203 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		925492 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		894277 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		564702 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Hs
		951377 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Hs
		925647 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Hs
		1031170 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		PTK7_HUMAN (4-527): 3.59e-35: 142: 14.13
+	Hs
		894276 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		PXDN_HUMAN (245-533): 1.24e-44: 171: 12.33
+	Hs
		1331019 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		ROBO1_HUMAN (333-538): 1.79e-18: 91.7: 8.92
+	Hs
		1294920 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Hs
		564764 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		ROBO1_HUMAN (333-538): 1.79e-18: 91.7: 8.92
+	Ce
		136794 CDC42_CAEEL (10-193): 3.51e-91: 266: 67.94		UNC89_CAEEL (251-441): 8.96e-11: 67.1: 12.81
+	Hs
		564645 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Hs
		925776 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		ROBO1_HUMAN (333-538): 1.79e-18: 91.7: 8.92
+	Hs
		951238 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Hs
		925521 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Hs
		894314 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Hs
		894044 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		MYLK_HUMAN (158-258): 4.39e-10: 64.7: 11.88