HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: VAMP8 (Q9BV40)
Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB)
Gene: VAMP8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 100
+	Hs
		850593 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		VAMP7_HUMAN (1-100): 1.25e-26: 99.2: 38.00
+	Hs
		1079435 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		1313459 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		VAMP8_HUMAN (1-100): 2.94e-24: 89.6: 100.00
+	Hs
		564456 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		VAMP7_HUMAN (1-100): 1.25e-26: 99.2: 38.00
+	Hs
		850558 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		VAMP7_HUMAN (1-100): 1.25e-26: 99.2: 38.00
+	Hs
		850556 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		VAMP7_HUMAN (1-100): 1.25e-26: 99.2: 38.00
+	Hs
		564545 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		850550 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		VAMP7_HUMAN (1-100): 1.25e-26: 99.2: 38.00
+	Hs
		951017 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		951283 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		VAMP8_HUMAN (1-100): 2.94e-24: 89.6: 100.00
+	Hs
		850552 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		VAMP7_HUMAN (1-100): 1.25e-26: 99.2: 38.00
+	Hs
		926199 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		VAMP2_HUMAN (6-82): 2.47e-23: 88: 35.07
+	Hs
		925304 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		925171 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		VAMP2_HUMAN (6-82): 2.47e-23: 88: 35.07
+	Hs
		894048 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		894374 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		VAMP8_HUMAN (1-100): 2.94e-24: 89.6: 100.00
+	Mm
		892719 CDC42_MOUSE (9-193): 1.09e-78: 235: 67.57		VAMP2_MOUSE (6-82): 2.47e-23: 88: 35.07
+	Hs
		893880 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		VAMP2_HUMAN (6-82): 2.47e-23: 88: 35.07
+	Hs
		900509 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		900359 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		VAMP2_HUMAN (6-82): 2.47e-23: 88: 35.07