HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: PACN2 (Q9UNF0)
Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) (SdpII)
Gene: PACSIN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	31871319, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 486
+	Hs
		1330988 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		PACN2_HUMAN (1-486): 1.94e-100: 311: 100.00
+	Hs
		951457 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		PACN2_HUMAN (1-486): 1.94e-100: 311: 100.00
+	Hs
		1330981 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		PACN3_HUMAN (6-485): 8.44e-67: 222: 41.04
+	Hs
		1075815 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		CIP4_HUMAN (12-465): 9.47e-47: 173: 15.03
+	Hs
		1001594 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		1301540 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		FNBP1_HUMAN (12-397): 7.86e-42: 159: 15.01
+	Hs
		564730 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		PACN3_HUMAN (6-485): 8.44e-67: 222: 41.04
+	Hs
		1021704 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		564542 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		CIP4_HUMAN (12-465): 9.47e-47: 173: 15.03
+	Hs
		564496 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Ce
		983034 CDC42_CAEEL (10-193): 3.51e-91: 266: 67.94		TOCA1_CAEEL (9-425): 6.09e-38: 148: 13.24
+	Hs
		950948 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		925230 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		564653 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		FNBP1_HUMAN (12-397): 7.86e-42: 159: 15.01
+	Hs
		951252 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		FNBP1_HUMAN (12-397): 7.86e-42: 159: 15.01
+	Hs
		564501 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		950955 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		925240 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		1132435 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		FBP1L_HUMAN (300-482): 7.32e-09: 60.2: 19.05
+	Hs
		925339 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		FBP1L_HUMAN (300-482): 7.32e-09: 60.2: 19.05