HitPredict

Interactor 1: HMGA1 (P17096)
High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein R)
Gene: HMGA1

Interactor 2: H2B2F (Q5QNW6)
Histone H2B type 2-F (H2B-clustered histone 18)
Gene: H2BC18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0030527 - structural constituent of chromatin
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 107 Hs			1 126
+	Hs
		565015 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B1M_HUMAN (1-126): 2.53e-55: 170: 95.24
+	Hs
		564845 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2BFS_HUMAN (1-126): 7.4e-55: 169: 96.03
+	Hs
		564850 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B1C_HUMAN (1-126): 6.35e-55: 169: 98.41
+	Hs
		564923 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B2E_HUMAN (1-126): 3.79e-55: 169: 97.62
+	Hs
		564990 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B1H_HUMAN (1-126): 3.18e-55: 169: 99.21
+	Hs
		564846 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B1D_HUMAN (1-126): 1.76e-54: 168: 97.62
+	Hs
		565016 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B1L_HUMAN (1-126): 1.29e-53: 166: 96.83
+	Hs
		564938 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B2C_HUMAN (1-96): 1.25e-44: 145: 88.54