HitPredict

Interactor 1: HMGA1 (P17096)
High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein R)
Gene: HMGA1

Interactor 2: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 34349018
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 107 Hs			1 130
+	Hs
		564989 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A1C_HUMAN (1-130): 5.62e-67: 200: 98.46
+	Hs
		391537 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		470258 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46
+	Hs
		564997 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A1H_HUMAN (1-128): 3.92e-66: 197: 98.44
+	Hs
		564959 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A2B_HUMAN (1-130): 1.54e-65: 196: 94.62
+	Hs
		555282 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81