HitPredict

Interactor 1: PTPC1 (A2A3K4)
Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-)
Gene: PTPDC1

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27432908, 28675297
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 754 Hs			1 246
+	Hs
		56523 PTPC1_HUMAN (1-754): 0: 1239: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		56525 PTPC1_HUMAN (1-754): 0: 1239: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		56507 PTPC1_HUMAN (1-754): 0: 1239: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		56522 PTPC1_HUMAN (1-754): 0: 1239: 100.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		56529 PTPC1_HUMAN (1-754): 0: 1239: 100.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		927549 TENS1_HUMAN (2-253): 3.02e-50: 193: 17.98		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Mm
		139359 PTEN_MOUSE (56-245): 2.03e-46: 172: 19.80		1433E_MOUSE (3-243): 4.39e-144: 405: 65.43
+	Hs
		910155 CC14A_HUMAN (16-246): 6.07e-42: 163: 19.11		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683811 CC14A_HUMAN (16-246): 6.07e-42: 163: 19.11		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Dm
		664615 Q7KMQ6_DROME (56-247): 1.84e-44: 169: 21.61		1433Z_DROME (2-246): 4.79e-141: 396: 78.78
+	Hs
		927656 CC14A_HUMAN (16-246): 6.07e-42: 163: 19.11		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		683433 TENS3_HUMAN (74-288): 4.23e-37: 152: 16.17		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		647379 CC14A_HUMAN (16-246): 6.07e-42: 163: 19.11		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		646992 TENS3_HUMAN (74-288): 4.23e-37: 152: 16.17		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		640212 PTN3_HUMAN (12-237): 7.75e-35: 144: 13.98		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		905257 CC14A_HUMAN (16-246): 6.07e-42: 163: 19.11		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		982618 CC14A_HUMAN (16-246): 6.07e-42: 163: 19.11		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		904702 TENS3_HUMAN (74-288): 4.23e-37: 152: 16.17		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		982129 TENS3_HUMAN (74-288): 4.23e-37: 152: 16.17		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		684109 TENS3_HUMAN (74-288): 4.23e-37: 152: 16.17		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62