Interactor 1: KAR3 (P17119)
Kinesin-like protein KAR3 (EC 5.6.1.4) (Nuclear fusion protein)
Gene: KAR3

Interactor 2: CIK1 (Q01649)
Spindle pole body-associated protein CIK1 (Chromosome instability and karyogamy protein 1)
Gene: CIK1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 10888675, 8106549, 25626168, 9632790, 25313961, 16085496, 27716509, 33044553, 22319456, 23388829, 24099757, 17382884
Identification Methods coimmunoprecipitation, two hybrid, cosedimentation through density gradient, affinity chromatography technology, biochemical, pull down, x-ray crystallography, molecular sieving
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Kinesin~Microtub_bd
Common GO terms GO:0000742 - karyogamy involved in conjugation with cellular fusion
GO:0000743 - nuclear migration involved in conjugation with cellular fusion
GO:0005634 - nucleus
GO:0005816 - spindle pole body
GO:0005881 - cytoplasmic microtubule
and 4 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 729
Sc

1 594
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024