HitPredict

Interactor 1: PHO85 (P17157)
Cyclin-dependent protein kinase PHO85 (EC 2.7.11.22) (Negative regulator of the PHO system) (Serine/threonine-protein kinase PHO85)
Gene: PHO85

Interactor 2: PCL1 (P24867)
PHO85 cyclin-1 (Cyclin HCS26) (G1/S-specific cyclin PCL1)
Gene: PCL1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 9032248, 7973730, 20489023, 16319894, 33217428, 23264631, 7973731
Identification Methods affinity chromatography technology, two hybrid, pull down, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_N~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0001676 - long-chain fatty acid metabolic process
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 5 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 305
Sc

1 279
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024