HitPredict

Interactor 1: PHO85 (P17157)
Cyclin-dependent protein kinase PHO85 (EC 2.7.11.22) (Negative regulator of the PHO system) (Serine/threonine-protein kinase PHO85)
Gene: PHO85

Interactor 2: PCL2 (P25693)
PHO85 cyclin-2 (Cyclin HCS26 homolog) (G1/S-specific cyclin PCL2)
Gene: PCL2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.922

The method score is based on:

Property	Details
Experiments	9032248, 10688190, 7973731, 20489023
Identification Methods	affinity chromatography technology, two hybrid, pull down, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Cyclin_N~Pkinase
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0001676 - long-chain fatty acid metabolic process GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005935 - cellular bud neck and 5 others more... GO:0030952 - establishment or maintenance of cytoskeleton polarity GO:0032878 - regulation of establishment or maintenance of cell polarity GO:0044843 - cell cycle G1/S phase transition GO:0051302 - regulation of cell division GO:0051726 - regulation of cell cycle
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	305
Sc

1	308

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024