HitPredict

Interactor 1: PHO85 (P17157)
Cyclin-dependent protein kinase PHO85 (EC 2.7.11.22) (Negative regulator of the PHO system) (Serine/threonine-protein kinase PHO85)
Gene: PHO85

Interactor 2: PCL9 (Q12477)
PHO85 cyclin-9
Gene: PCL9

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.911

The method score is based on:

Property	Details
Experiments	10688190, 9032248, 9593297, 20489023
Identification Methods	two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Cyclin_N~Pkinase
Common GO terms	GO:0000082 - G1/S transition of mitotic cell cycle GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005935 - cellular bud neck GO:0006355 - regulation of DNA-templated transcription and 3 others more... GO:0006357 - regulation of transcription by RNA polymerase II GO:0032878 - regulation of establishment or maintenance of cell polarity GO:0051726 - regulation of cell cycle
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	305
Sc

1	304

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024