HitPredict

Interactor 1: VATA (P17255)
V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (Vacuolar proton pump subunit A) [Cleaved into: Endonuclease PI-SceI (EC 3.1.-.-) (Sce VMA intein) (VMA1-derived endonuclease) (VDE)]
Gene: VMA1

Interactor 2: SIS1 (P25294)
Protein SIS1
Gene: SIS1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33326013, 37845327
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1071 Sc			1 352
+	Hs
		636815 ATPA_HUMAN (582-1066): 5.09e-145: 447: 17.28		DNJA1_HUMAN (1-352): 2.53e-121: 357: 28.93
+	Sc
		423769 ATPA_YEAST (556-1066): 1.15e-140: 435: 18.15		SIS1_YEAST (1-352): 6.96e-105: 313: 100.00
+	Sc
		341935 ATPB_YEAST (716-992): 5.1e-83: 280: 24.91		SIS1_YEAST (1-352): 6.96e-105: 313: 100.00
+	Ec
		442681 ATPB_ECOLI (728-983): 1.48e-80: 272: 26.56		DNAJ_ECOLI (2-351): 3.01e-107: 320: 26.48
+	Sc
		555844 VATB_YEAST (767-1005): 8.09e-16: 84: 25.98		MAS5_YEAST (1-352): 1.41e-111: 332: 28.13
+	Sc
		555832 VATB_YEAST (767-1005): 8.09e-16: 84: 25.98		SIS1_YEAST (1-352): 6.96e-105: 313: 100.00