HitPredict

Interactor 1: JUNB (P17275)
Transcription factor JunB (Transcription factor AP-1 subunit JunB)
Gene: JUNB

Interactor 2: ATF4 (P18848)
Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (Tax-responsive enhancer element-binding protein 67) (TaxREB67)
Gene: ATF4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

The method score is based on:

Property	Details
Experiments	21988832, 23661758
Identification Methods	two hybrid, fluorescent resonance energy transfer
Interaction Type	direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	bZIP_1~bZIP_1
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0003677 - DNA binding and 7 others more... GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0090575 - RNA polymerase II transcription regulator complex GO:0140467 - integrated stress response signaling GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	347
Hs

1	351

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024