HitPredict

Interactor 1: ITA2 (P17301)
Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b)
Gene: ITGA2

Interactor 2: CD9 (P21926)
CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9)
Gene: CD9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	26686862
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0007155 - cell adhesion GO:0009897 - external side of plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1181 Hs			1 228
+	Hs
		566869 ITA2_HUMAN (1-1181): 0: 1250: 100.00		TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64
+	Hs
		566893 ITA2_HUMAN (1-1181): 0: 1250: 100.00		TSN14_HUMAN (11-225): 6.56e-49: 162: 24.02
+	Hs
		880206 ITA1_HUMAN (1-1169): 0: 1134: 38.84		CD81_HUMAN (1-225): 2.3e-53: 173: 43.59
+	Hs
		91491 E7ESP4_HUMAN (1-942): 0: 1025: 100.00		CD81_HUMAN (1-225): 2.3e-53: 173: 43.59
+	Hs
		595498 ITAL_HUMAN (12-1169): 0: 860: 24.61		CD82_HUMAN (4-224): 3.81e-46: 155: 24.23
+	Hs
		602219 ITA3_HUMAN (2-512): 5.18e-65: 241: 18.32		CD9_HUMAN (1-228): 5.13e-61: 192: 100.00
+	Hs
		602217 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		CD9_HUMAN (1-228): 5.13e-61: 192: 100.00
+	Hs
		639879 ITA3_HUMAN (2-512): 5.18e-65: 241: 18.32		TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64
+	Hs
		639875 ITA3_HUMAN (2-512): 5.18e-65: 241: 18.32		CD151_HUMAN (3-222): 5.02e-51: 167: 30.08
+	Hs
		639894 ITA3_HUMAN (2-512): 5.18e-65: 241: 18.32		TSN14_HUMAN (11-225): 6.56e-49: 162: 24.02
+	Hs
		613235 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64
+	Hs
		613229 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		CD81_HUMAN (1-225): 2.3e-53: 173: 43.59
+	Hs
		613224 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		CD151_HUMAN (3-222): 5.02e-51: 167: 30.08
+	Hs
		50294 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		TSN11_HUMAN (10-223): 3.63e-50: 165: 25.83
+	Hs
		326269 ITA3_HUMAN (2-512): 5.18e-65: 241: 18.32		TSN12_HUMAN (1-217): 2.08e-43: 149: 22.13
+	Hs
		156133 ITA3_HUMAN (2-512): 5.18e-65: 241: 18.32		TSN4_HUMAN (4-223): 8.35e-43: 146: 25.53
+	Hs
		50296 ITA7_HUMAN (5-512): 4.56e-57: 218: 17.52		TSN11_HUMAN (10-223): 3.63e-50: 165: 25.83
+	Hs
		156132 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		TSN4_HUMAN (4-223): 8.35e-43: 146: 25.53
+	Mm
		192879 ITA3_MOUSE (1-443): 1.48e-57: 218: 15.60		CD151_MOUSE (4-222): 8.49e-44: 149: 30.61
+	Hs
		613274 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		TSN18_HUMAN (5-222): 2.95e-33: 121: 28.29