HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: EPHA3 (P29320)
Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)
Gene: EPHA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 983
+	Hs
		566985 CXA1_HUMAN (1-382): 0: 545: 100.00		EPHA4_HUMAN (8-983): 0: 1164: 62.40
+	Hs
		566984 CXA1_HUMAN (1-382): 0: 545: 100.00		EPHB3_HUMAN (24-983): 0: 1111: 56.17
+	Hs
		566935 CXA1_HUMAN (1-382): 0: 545: 100.00		EPHA2_HUMAN (27-983): 0: 1061: 50.47
+	Hs
		434822 CXB1_HUMAN (3-285): 8.15e-116: 339: 38.62		EPHB1_HUMAN (28-983): 0: 1162: 55.69
+	Hs
		1072544 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		EPHA7_HUMAN (6-979): 0: 1198: 61.46
+	Hs
		872409 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		EPHB3_HUMAN (24-983): 0: 1111: 56.17
+	Hs
		665269 CXB7_HUMAN (4-234): 1.64e-104: 309: 41.81		EPHA2_HUMAN (27-983): 0: 1061: 50.47
+	Hs
		665282 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		EPHA2_HUMAN (27-983): 0: 1061: 50.47
+	Hs
		434812 CXB1_HUMAN (3-285): 8.15e-116: 339: 38.62		EPHA1_HUMAN (7-973): 0: 949: 42.52
+	Hs
		435527 CXA1_HUMAN (1-382): 0: 545: 100.00		IGF1R_HUMAN (366-883): 1.6e-139: 453: 30.02
+	Hs
		411289 CXA1_HUMAN (1-382): 0: 545: 100.00		INSR_HUMAN (375-880): 6.57e-136: 444: 30.32
+	Hs
		411435 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		INSR_HUMAN (375-880): 6.57e-136: 444: 30.32
+	Hs
		412232 CXB7_HUMAN (4-234): 1.64e-104: 309: 41.81		FYN_HUMAN (615-879): 1.08e-64: 229: 44.20