HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	19835873, 34079125, 21554242, 25070368
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016324 - apical plasma membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 896
+	Mm
		613305 CXA1_MOUSE (1-382): 0: 544: 97.38		EPS15_MOUSE (1-896): 6.54e-132: 419: 88.54
+	Hs
		567346 CXA1_HUMAN (1-382): 0: 545: 100.00		MRCKB_HUMAN (223-886): 2.4e-41: 167: 12.72
+	Hs
		567074 CXA1_HUMAN (1-382): 0: 545: 100.00		ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61
+	Rn
		435376 CXA1_RAT (1-382): 0: 546: 97.64		EHD1_RAT (17-102): 8.82e-16: 83.5: 32.56
+	Hs
		522587 CXA1_HUMAN (1-382): 0: 545: 100.00		MYH7_HUMAN (256-608): 1.36e-14: 80.6: 11.14
+	Hs
		1078861 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61