HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 100
+	Hs
		261635 CXA1_HUMAN (1-382): 0: 545: 100.00		VAMP4_HUMAN (3-82): 3.5e-25: 93.5: 40.00
+	Hs
		566999 CXA1_HUMAN (1-382): 0: 545: 100.00		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		263163 CXA1_HUMAN (1-382): 0: 545: 100.00		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56
+	Hs
		263193 CXA8_HUMAN (1-382): 1.55e-135: 395: 37.81		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56
+	Hs
		306772 CXA8_HUMAN (1-382): 1.55e-135: 395: 37.81		VAMP5_HUMAN (11-80): 1.96e-20: 80.4: 38.57
+	Hs
		263126 CXB6_HUMAN (3-253): 2.52e-123: 358: 42.19		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56
+	Hs
		263125 CXB5_HUMAN (3-280): 1.3e-109: 323: 33.57		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56
+	Hs
		1079370 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		261689 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		VAMP4_HUMAN (3-82): 3.5e-25: 93.5: 40.00
+	Hs
		926229 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		263285 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56