HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: MRCKA (Q5VT25)
Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)
Gene: CDC42BPA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 1732
+	Hs
		567346 CXA1_HUMAN (1-382): 0: 545: 100.00		MRCKB_HUMAN (1-1731): 0: 1417: 60.38
+	Hs
		1137881 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		MRCKA_HUMAN (1-1732): 0: 1615: 100.00
+	Hs
		566939 CXA1_HUMAN (1-382): 0: 545: 100.00		AKT2_HUMAN (13-391): 2.91e-129: 414: 30.65
+	Hs
		566938 CXA1_HUMAN (1-382): 0: 545: 100.00		AKT1_HUMAN (13-404): 1.23e-128: 413: 31.51
+	Hs
		567321 CXA1_HUMAN (1-382): 0: 545: 100.00		TNIK_HUMAN (53-905): 4.35e-97: 346: 15.60
+	Hs
		567064 CXA1_HUMAN (1-382): 0: 545: 100.00		STK38_HUMAN (66-404): 1.24e-89: 302: 45.07
+	Hs
		254446 CXA1_HUMAN (1-382): 0: 545: 100.00		ROCK2_HUMAN (373-1052): 1.4e-22: 108: 12.07