HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34079125, 28877994
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0030054 - cell junction
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 1121
+	Hs
		567277 CXA1_HUMAN (1-382): 0: 545: 100.00		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Rn
		435368 CXA1_RAT (1-382): 0: 546: 97.64		NEDD4_RAT (11-97): 3.59e-19: 95.8: 25.93
+	Hs
		567301 CXA1_HUMAN (1-382): 0: 545: 100.00		WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91
+	Hs
		567219 CXA1_HUMAN (1-382): 0: 545: 100.00		ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49
+	Hs
		566962 CXA1_HUMAN (1-382): 0: 545: 100.00		NEDD4_HUMAN (11-95): 1.03e-15: 84.6: 24.17
+	Hs
		1230378 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		1230404 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91