HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: VRK2 (Q86Y07)
Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)
Gene: VRK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0007165 - signal transduction
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 508
+	Hs
		566931 CXA1_HUMAN (1-382): 0: 545: 100.00		MARK3_HUMAN (22-469): 8.37e-112: 350: 14.22
+	Hs
		567131 CXA1_HUMAN (1-382): 0: 545: 100.00		MARK2_HUMAN (3-485): 1.13e-111: 350: 13.73
+	Hs
		566939 CXA1_HUMAN (1-382): 0: 545: 100.00		AKT2_HUMAN (5-372): 9.14e-110: 336: 14.65
+	Hs
		566969 CXA1_HUMAN (1-382): 0: 545: 100.00		KC1D_HUMAN (21-465): 9.4e-99: 305: 22.37
+	Hs
		734383 CXA5_HUMAN (1-382): 2.28e-140: 405: 40.40		VRK2_HUMAN (1-508): 1.87e-117: 357: 100.00
+	Hs
		1205022 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		VRK2_HUMAN (1-508): 1.87e-117: 357: 100.00
+	Hs
		1183071 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		MARK2_HUMAN (3-485): 1.13e-111: 350: 13.73
+	Hs
		647924 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		MARK3_HUMAN (22-469): 8.37e-112: 350: 14.22
+	Hs
		1161193 CXB7_HUMAN (4-234): 1.64e-104: 309: 41.81		KC1G3_HUMAN (24-408): 2.13e-105: 323: 23.65