HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: PACE1 (Q8IZE3)
Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3)
Gene: SCYL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0008104 - protein localization
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 742
+	Hs
		566931 CXA1_HUMAN (1-382): 0: 545: 100.00		MARK3_HUMAN (2-590): 9.3e-123: 386: 11.03
+	Hs
		567222 CXA1_HUMAN (1-382): 0: 545: 100.00		SCYL1_HUMAN (13-423): 6.24e-115: 367: 27.44
+	Hs
		567131 CXA1_HUMAN (1-382): 0: 545: 100.00		MARK2_HUMAN (2-672): 1.7e-114: 365: 11.68
+	Hs
		567117 CXA1_HUMAN (1-382): 0: 545: 100.00		SCYL2_HUMAN (14-456): 1.95e-86: 294: 19.37
+	Hs
		1224243 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		PACE1_HUMAN (1-742): 1.18e-176: 525: 100.00
+	Hs
		647924 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		MARK3_HUMAN (2-590): 9.3e-123: 386: 11.03
+	Hs
		1230335 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		SCYL1_HUMAN (13-423): 6.24e-115: 367: 27.44
+	Hs
		1183071 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		MARK2_HUMAN (2-672): 1.7e-114: 365: 11.68
+	Hs
		128967 CXA1_HUMAN (1-382): 0: 545: 100.00		PLK4_HUMAN (42-246): 1.52e-16: 86.4: 21.05