HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005102 - signaling receptor binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 232
+	Hs
		566990 CXA1_HUMAN (1-382): 0: 545: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		566980 CXA1_HUMAN (1-382): 0: 545: 100.00		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		566998 CXA1_HUMAN (1-382): 0: 545: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		566989 CXA1_HUMAN (1-382): 0: 545: 100.00		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		545196 CXA1_HUMAN (1-382): 0: 545: 100.00		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		566992 CXA1_HUMAN (1-382): 0: 545: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		567008 CXA1_HUMAN (1-382): 0: 545: 100.00		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		436147 CXA1_HUMAN (1-382): 0: 545: 100.00		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		566996 CXA1_HUMAN (1-382): 0: 545: 100.00		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		734406 CXG1_HUMAN (4-373): 1.81e-130: 381: 32.49		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		918903 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		RAB1A_HUMAN (1-229): 3.11e-78: 235: 21.21
+	Hs
		914204 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88