HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: MARK1 (Q9P0L2)
Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)
Gene: MARK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001764 - neuron migration GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0010628 - positive regulation of gene expression GO:0010629 - negative regulation of gene expression
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 795
+	Hs
		567131 CXA1_HUMAN (1-382): 0: 545: 100.00		MARK2_HUMAN (2-795): 0: 668: 63.76
+	Hs
		566931 CXA1_HUMAN (1-382): 0: 545: 100.00		MARK3_HUMAN (1-795): 0: 664: 63.86
+	Hs
		734395 CXA5_HUMAN (1-382): 2.28e-140: 405: 40.40		MARK1_HUMAN (1-795): 0: 775: 100.00
+	Hs
		1183071 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		MARK2_HUMAN (2-795): 0: 668: 63.76
+	Hs
		647924 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		MARK3_HUMAN (1-795): 0: 664: 63.86