HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: TNIK (Q9UKE5)
TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016324 - apical plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 1360
+	Hs
		567165 CXA1_HUMAN (1-382): 0: 545: 100.00		MINK1_HUMAN (1-1360): 0: 1051: 60.43
+	Hs
		324735 CXA1_HUMAN (1-382): 0: 545: 100.00		M4K4_HUMAN (1-1360): 0: 970: 59.11
+	Hs
		1230271 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		MINK1_HUMAN (1-1360): 0: 1051: 60.43
+	Hs
		567105 CXA1_HUMAN (1-382): 0: 545: 100.00		MRCKA_HUMAN (12-1330): 0: 690: 13.75
+	Hs
		567346 CXA1_HUMAN (1-382): 0: 545: 100.00		MRCKB_HUMAN (15-1330): 0: 661: 15.04
+	Hs
		1137881 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		MRCKA_HUMAN (12-1330): 0: 690: 13.75
+	Hs
		566931 CXA1_HUMAN (1-382): 0: 545: 100.00		MARK3_HUMAN (3-675): 1.72e-124: 406: 16.37
+	Hs
		566939 CXA1_HUMAN (1-382): 0: 545: 100.00		AKT2_HUMAN (3-352): 5.78e-123: 392: 22.87
+	Hs
		567345 CXA1_HUMAN (1-382): 0: 545: 100.00		M4K5_HUMAN (19-373): 7.89e-73: 263: 40.38
+	Hs
		647924 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		MARK3_HUMAN (3-675): 1.72e-124: 406: 16.37