HitPredict

Interactor 1: AP2A1 (P17426)
AP-2 complex subunit alpha-1 (100 kDa coated vesicle protein A) (Adaptor protein complex AP-2 subunit alpha-1) (Adaptor-related protein complex 2 subunit alpha-1) (Alpha-adaptin A) (Alpha1-adaptin) (Clathrin assembly protein complex 2 alpha-A large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit)
Gene: AP2A1

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28469556
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0044877 - protein-containing complex binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 977 Mm			1 1730
+	Mm
		193240 AP1B1_MOUSE (36-972): 0: 686: 17.37		SHAN3_MOUSE (1-1730): 0: 626: 100.00
+	Hs
		925995 AP2B1_HUMAN (36-972): 0: 692: 16.89		SHAN3_HUMAN (1-1730): 0: 601: 95.21
+	Hs
		321591 AP2A1_HUMAN (1-977): 0: 909: 97.75		MIB1_HUMAN (187-625): 7.14e-50: 195: 10.66
+	Hs
		302181 AP2A2_HUMAN (1-977): 0: 839: 77.28		MIB1_HUMAN (187-625): 7.14e-50: 195: 10.66
+	Hs
		166867 AP2A2_HUMAN (1-977): 0: 839: 77.28		ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60
+	Hs
		925936 AP2B1_HUMAN (36-972): 0: 692: 16.89		MIB1_HUMAN (187-625): 7.14e-50: 195: 10.66
+	Hs
		166905 AP2B1_HUMAN (36-972): 0: 692: 16.89		ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60
+	Hs
		926051 AP2B1_HUMAN (36-972): 0: 692: 16.89		KDIS_HUMAN (258-430): 1.28e-21: 105: 16.19