HitPredict

Interactor 1: AP2A1 (P17426)
AP-2 complex subunit alpha-1 (100 kDa coated vesicle protein A) (Adaptor protein complex AP-2 subunit alpha-1) (Adaptor-related protein complex 2 subunit alpha-1) (Alpha-adaptin A) (Alpha1-adaptin) (Clathrin assembly protein complex 2 alpha-A large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit)
Gene: AP2A1

Interactor 2: AP2B1 (Q9DBG3)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29262337
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Adaptin_N~Adaptin_N, Alpha_adaptinC2~Alpha_adaptin_C, Alpha_adaptinC2~Alpha_adaptinC2, Alpha_adaptinC2~B2-adapt-app_C
Common GO terms GO:0006886 - intracellular protein transport
GO:0009898 - cytoplasmic side of plasma membrane
GO:0016192 - vesicle-mediated transport
GO:0030122 - AP-2 adaptor complex
GO:0044877 - protein-containing complex binding
and 3 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 977
Mm

1 937
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ At
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024