Interactor 1: SPI1 (P17433)
Transcription factor PU.1 (31 kDa-transforming protein) (SFFV proviral integration 1 protein)
Gene: SPI1

Interactor 2: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.700

The method score is based on:

Property Details
Experiments 16707500, 16183743, 18799728, 20405120, 21757649
Identification Methods anti tag coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0002314 - germinal center B cell differentiation
and 9 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 272
Mm

1 424
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024