HitPredict

Interactor 1: SPI1 (P17433)
Transcription factor PU.1 (31 kDa-transforming protein) (SFFV proviral integration 1 protein)
Gene: SPI1

Interactor 2: IRF4 (Q64287)
Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP)
Gene: IRF4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.660

The method score is based on:

Property Details
Experiments 11133986, 19592658, 16093364
Identification Methods pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
and 7 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 272
Mm

1 450
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024