HitPredict

Interactor 1: SPI1 (P17433)
Transcription factor PU.1 (31 kDa-transforming protein) (SFFV proviral integration 1 protein)
Gene: SPI1

Interactor 2: TRI33 (Q99PP7)
E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)
Gene: Trim33

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	21474105
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 272 Mm			1 1142
+	Hs
		507528 ERG_HUMAN (57-271): 1.46e-45: 161: 20.08		TRI33_HUMAN (1-1142): 0: 639: 94.75
+	Mm
		101420 SPI1_MOUSE (1-272): 5.91e-131: 373: 100.00		F8VPR5_MOUSE (529-1076): 1.78e-64: 242: 15.11
+	Hs
		572564 SPI1_HUMAN (1-272): 7.11e-124: 355: 87.87		Q15156_HUMAN (96-497): 9.05e-72: 257: 19.54
+	Hs
		170228 ERG_HUMAN (57-271): 1.46e-45: 161: 20.08		TIF1A_HUMAN (118-1142): 8.17e-139: 448: 45.23
+	Hs
		170274 ELF1_HUMAN (95-256): 3.23e-39: 146: 26.22		TIF1A_HUMAN (118-1142): 8.17e-139: 448: 45.23
+	Hs
		170240 ETS1_HUMAN (122-254): 9.82e-40: 145: 29.85		TIF1A_HUMAN (118-1142): 8.17e-139: 448: 45.23
+	Mm
		567562 SPI1_MOUSE (1-272): 5.91e-131: 373: 100.00		PML_MOUSE (90-664): 7.84e-58: 218: 15.74
+	Hs
		170329 ELF3_HUMAN (130-260): 5.44e-38: 138: 25.56		TIF1A_HUMAN (118-1142): 8.17e-139: 448: 45.23
+	Hs
		572540 SPI1_HUMAN (1-272): 7.11e-124: 355: 87.87		PML_HUMAN (96-663): 7.26e-54: 205: 16.17
+	Mm
		101434 GABPA_MOUSE (52-254): 4.88e-68: 219: 28.16		F8VPR5_MOUSE (529-1076): 1.78e-64: 242: 15.11
+	Mm
		542771 ETS2_MOUSE (93-254): 2.54e-42: 152: 28.22		CBP_MOUSE (529-1076): 1.05e-64: 243: 15.11
+	Mm
		101419 ETS2_MOUSE (93-254): 2.54e-42: 152: 28.22		F8VPR5_MOUSE (529-1076): 1.78e-64: 242: 15.11
+	Hs
		507480 ERG_HUMAN (57-271): 1.46e-45: 161: 20.08		CBP_HUMAN (533-1076): 1.35e-61: 233: 15.00
+	Hs
		542756 ETS2_HUMAN (59-254): 1.25e-43: 155: 24.63		CBP_HUMAN (533-1076): 1.35e-61: 233: 15.00
+	Mm
		649230 ETS1_MOUSE (122-254): 1.05e-39: 144: 29.85		CBP_MOUSE (529-1076): 1.05e-64: 243: 15.11
+	Mm
		101425 ETS1_MOUSE (122-254): 1.05e-39: 144: 29.85		F8VPR5_MOUSE (529-1076): 1.78e-64: 242: 15.11
+	Hs
		542053 ETS1_HUMAN (122-254): 9.82e-40: 145: 29.85		CBP_HUMAN (533-1076): 1.35e-61: 233: 15.00
+	Hs
		507502 ERG_HUMAN (57-271): 1.46e-45: 161: 20.08		TRIM8_HUMAN (136-669): 7.79e-58: 211: 15.06
+	Hs
		668714 ELF2_HUMAN (72-255): 9.07e-44: 158: 24.19		PML_HUMAN (96-663): 7.26e-54: 205: 16.17
+	Hs
		507364 ERG_HUMAN (57-271): 1.46e-45: 161: 20.08		RO52_HUMAN (229-607): 1.11e-54: 200: 13.75