Interactor 1: CUL4B (A2A432)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: RBX1 (P62878)
E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (E3 ubiquitin-protein transferase RBX1) (RING finger protein 75) (RING-box protein 1) (Rbx1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed]
Gene: RBX1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27113764
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~zf-rbx1, Cullin_Nedd8~zf-rbx1
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0006974 - DNA damage response
and 5 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 970
Mm

1 108
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Mm
+ Hs
+ At
+ At
+ At
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm
+ Dm
+ At
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024