Interactor 1: CUL4B (A2A432)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: DDB1 (Q3U1J4)
DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)
Gene: DDB1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 27113764, 30442713, 33524014, 34161765
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CPSF_A~Cullin, Cullin~MMS1_N
Common GO terms GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0006974 - DNA damage response
and 7 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 970
Mm

1 1140
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Sp
+ Hs
+ Sp
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024