Interactor 1: TAL1 (P17542)
T-cell acute lymphocytic leukemia protein 1 (TAL-1) (Class A basic helix-loop-helix protein 17) (bHLHa17) (Stem cell protein) (T-cell leukemia/lymphoma protein 5)
Gene: TAL1

Interactor 2: GATA2 (P23769)
Endothelial transcription factor GATA-2 (GATA-binding protein 2)
Gene: GATA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.43 0.60 0.508

The method score is based on:

Property Details
Experiments 7568177
Identification Methods two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003682 - chromatin binding
GO:0003700 - DNA-binding transcription factor activity
and 9 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 331
Hs

1 480
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024