HitPredict

Interactor 1: TAL1 (P17542)
T-cell acute lymphocytic leukemia protein 1 (TAL-1) (Class A basic helix-loop-helix protein 17) (bHLHa17) (Stem cell protein) (T-cell leukemia/lymphoma protein 5)
Gene: TAL1

Interactor 2: ID4 (P47928)
DNA-binding protein inhibitor ID-4 (Class B basic helix-loop-helix protein 27) (bHLHb27) (Inhibitor of DNA binding 4) (Inhibitor of differentiation 4)
Gene: ID4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.798

The method score is based on:

Property Details
Experiments 33961781, 35140242
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0046983 - protein dimerization activity
and 1 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 331
Hs

1 161
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Last updated: 15 Jul 2024