HitPredict

Interactor 1: ATF7 (P17544)
Cyclic AMP-dependent transcription factor ATF-7 (cAMP-dependent transcription factor ATF-7) (Activating transcription factor 7) (Transcription factor ATF-A)
Gene: ATF7

Interactor 2: ARI1 (Q9Y4X5)
E3 ubiquitin-protein ligase ARIH1 (EC 2.3.2.31) (H7-AP2) (HHARI) (Monocyte protein 6) (MOP-6) (Protein ariadne-1 homolog) (ARI-1) (UbcH7-binding protein) (UbcM4-interacting protein) (Ubiquitin-conjugating enzyme E2-binding protein 1)
Gene: ARIH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 27565346, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 483 Hs			1 557
+	Hs
		547863 ATF2_HUMAN (1-475): 1.31e-81: 263: 54.97		ARI1_HUMAN (1-557): 0: 610: 100.00
+	Hs
		973657 CREB5_HUMAN (1-433): 5.82e-65: 220: 36.92		ARI1_HUMAN (1-557): 0: 610: 100.00
+	Hs
		402673 JUN_HUMAN (94-409): 4.25e-45: 162: 15.89		ARI1_HUMAN (1-557): 0: 610: 100.00
+	Hs
		566803 JUNB_HUMAN (68-403): 5.95e-43: 157: 16.10		ARI1_HUMAN (1-557): 0: 610: 100.00
+	Hs
		579166 ATF1_HUMAN (110-383): 5.11e-32: 125: 15.33		ARI1_HUMAN (1-557): 0: 610: 100.00
+	Hs
		557010 CREB1_HUMAN (89-383): 4.8e-27: 112: 15.25		ARI1_HUMAN (1-557): 0: 610: 100.00
+	Hs
		568110 JUND_HUMAN (94-408): 1.06e-26: 112: 16.67		ARI1_HUMAN (1-557): 0: 610: 100.00
+	Hs
		973598 CREB5_HUMAN (1-433): 5.82e-65: 220: 36.92		R144B_HUMAN (159-382): 6.89e-58: 197: 25.97
+	Hs
		228158 CR3L4_HUMAN (137-460): 1.67e-31: 126: 12.50		PRKN_HUMAN (151-388): 3.75e-55: 194: 22.10
+	Hs
		226439 CREB1_HUMAN (89-383): 4.8e-27: 112: 15.25		PRKN_HUMAN (151-388): 3.75e-55: 194: 22.10