Interactor 1: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Interactor 2: DRD1 (P21728)
D(1A) dopamine receptor (Dopamine D1 receptor)
Gene: DRD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 7609904
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0043197 - dendritic spine
GO:0098978 - glutamatergic synapse
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 351
Hs

1 446
+ Mm
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024