HitPredict

Interactor 1: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Interactor 2: KAPCG (P22612)
cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11)
Gene: PRKACG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 33961781, 23455922
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0003091 - renal water homeostasis
GO:0004674 - protein serine/threonine kinase activity
GO:0004679 - AMP-activated protein kinase activity
GO:0004691 - cAMP-dependent protein kinase activity
GO:0005524 - ATP binding
and 9 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 351
Hs

1 351
+ Hs
+ Hs
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+ Dm
+ Hs
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+ Mm
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+ Mm
+ Hs
+ Ce
+ Hs
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+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024