HitPredict

Interactor 1: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Interactor 2: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	35271311, 23455922
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 89
+	Hs
		568762 KAPCA_HUMAN (1-351): 9.98e-166: 467: 100.00		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		610709 KAPCB_HUMAN (1-351): 7.27e-164: 463: 92.88		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		610764 KAPCB_HUMAN (1-351): 7.27e-164: 463: 92.88		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		609658 KAPCG_HUMAN (1-351): 2.31e-162: 459: 82.91		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		609686 KAPCG_HUMAN (1-351): 2.31e-162: 459: 82.91		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26