Interactor 1: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.708

The method score is based on:

Property Details
Experiments 18178962, 20133937, 12628924, 9150141
Identification Methods affinity chromatography technology, enzymatic study, pull down, experimental interaction detection, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019221 - cytokine-mediated signaling pathway
and 3 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 351
Hs

1 551
+ Hs
+ Rn
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024