HitPredict

Interactor 1: CAN2 (P17655)
Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain large polypeptide L2) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain)
Gene: CAPN2

Interactor 2: KCTD7 (Q96MP8)
BTB/POZ domain-containing protein KCTD7
Gene: KCTD7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	36964131
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	BTB_2~EF-hand_8
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 700 Hs			1 289
+	Hs
		427919 CAN1_HUMAN (3-700): 0: 915: 62.20		KCTD7_HUMAN (1-289): 2.6e-108: 317: 100.00
+	Mm
		139005 CAN2_MOUSE (1-700): 0: 941: 93.86		BACD1_MOUSE (13-216): 5.46e-48: 164: 27.27
+	Hs
		1154464 CAN13_HUMAN (21-700): 0: 609: 29.57		KCTD7_HUMAN (1-289): 2.6e-108: 317: 100.00
+	Hs
		180619 CAN5_HUMAN (24-521): 0: 564: 35.29		KCTD7_HUMAN (1-289): 2.6e-108: 317: 100.00
+	Hs
		275506 CAN15_HUMAN (5-495): 4.97e-152: 470: 24.95		KCTD7_HUMAN (1-289): 2.6e-108: 317: 100.00
+	Hs
		1297996 CAN7_HUMAN (61-516): 2.67e-119: 377: 22.04		KCTD7_HUMAN (1-289): 2.6e-108: 317: 100.00
+	Hs
		1045953 CAN7_HUMAN (61-516): 2.67e-119: 377: 22.04		BACD2_HUMAN (23-230): 7.2e-43: 150: 23.70
+	Hs
		1045924 Q7Z479_HUMAN (61-516): 6.84e-119: 376: 22.04		BACD2_HUMAN (23-230): 7.2e-43: 150: 23.70
+	Hs
		385883 CPNS1_HUMAN (498-700): 1.57e-56: 195: 42.86		KCTD7_HUMAN (1-289): 2.6e-108: 317: 100.00
+	Hs
		1297992 CAN10_HUMAN (354-524): 3.56e-12: 71.6: 26.32		KCTD7_HUMAN (1-289): 2.6e-108: 317: 100.00